产品详情
简单介绍:
Human LIF protein (Recombinant) (STJP000233)
详情介绍:
Host: | CHO cells |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human LIF-protein was developed from cho cells. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS pH.5. |
Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: | Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The ED (50) was determined by the proliferation of Human TF-1 cells and was found to be <.1 ng="" ml.="" na<="" td=""> |
Gene Symbol: | LIF |
Gene ID: | 3976 |
Uniprot ID: | LIF_HUMAN |
Immunogen Region: | Mature chain |
Immunogen: | Optimized DNA sequence encoding Human LIF mature chain was expressed in CHO Cells NA |
Immunogen Sequence: | MKVLAAGVVP LLLVLHWKHG AGSPLPITPV NATCAIRHPC HNNLMNQIRS QLAQLNGSAN ALFILYYTAQ GEPFPNNLDK LCGPNVTDFP PFHANGTEKA KLVELYRIVV YLGTSLGNIT RDQKILNPSA LSLHSKLNAT ADILRGLLSN VLCRLCSKYH VGHVDVTYGP DTSGKDVFQK KKLGCQLLGK YKQIIAVLAQ AF NA |
Function | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
Protein Name | Leukemia Inhibitory Factor Lif Differentiation-Stimulating Factor D Factor Melanoma-Derived Lpl Inhibitor Mlpli Emfilermin |
Database Links | Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 Reactome: R-HSA-6788467 |
Cellular Localisation | Secreted |
Alternative Protein Names | Leukemia Inhibitory Factor protein Lif protein Differentiation-Stimulating Factor protein D Factor protein Melanoma-Derived Lpl Inhibitor protein Mlpli protein Emfilermin protein LIF protein HILDA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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