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  • 产品名称：Human LILRA4/CD85g protein (Recombinant) (C-His & Avi) {Biotin} (STJP002414)

  • 产品型号：STJP002414-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human LILRA4/CD85g protein (Recombinant) (C-His & Avi) {Biotin} (STJP002414)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human LILRA4/CD85g-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Gene Symbol: LILRA4
Gene ID: 23547
Uniprot ID: LIRA4_HUMAN
Immunogen Region: Glu24-Asn446
Immunogen: Recombinant Biotinylated Human LILRA4/CD85g Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.；It contains Glu24-Asn446.
Function Functions coreceptor to limit the innate immune responses to viral infections.signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 4
Cd85 Antigen-Like Family Member G
Immunoglobulin-Like Transcript 7
Ilt-7
Cd Antigen Cd85g
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 4 protein
Cd85 Antigen-Like Family Member G protein
Immunoglobulin-Like Transcript 7 protein
Ilt-7 protein
Cd Antigen Cd85g protein
LILRA4 protein
ILT7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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