产品详情
简单介绍:
LILRB3 Positive Control for STJ501608 peptide (STJ504348)
详情介绍:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | LILRB3 Positive Control for STJ501608 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | LILRB3 |
Gene ID: | 102725035/107987462 |
Uniprot ID: | LIRB3_HUMAN |
Specificity: | This is positive control is recommended for use in combination with LILRB3 antibody STJ501608. |
Tissue Specificity | Detected in monocytes and B-cells. |
Post Translational Modifications | Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2. |
Function | May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). |
Peptide Name | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 Lir-3 Leukocyte Immunoglobulin-Like Receptor 3 Cd85 Antigen-Like Family Member A Immunoglobulin-Like Transcript 5 Ilt-5 Monocyte Inhibitory Receptor Hl9 Cd Antigen Cd85a |
Database Links | Reactome: R-HSA-198933 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Peptide Names | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 protein Lir-3 protein Leukocyte Immunoglobulin-Like Receptor 3 protein Cd85 Antigen-Like Family Member A protein Immunoglobulin-Like Transcript 5 protein Ilt-5 protein Monocyte Inhibitory Receptor Hl9 protein Cd Antigen Cd85a protein LILRB3 protein ILT5 protein LIR3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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