产品详情
查看大图

  • 产品名称：Human MADCAM1 protein (Recombinant) (C-His) (STJP002437)

  • 产品型号：STJP002437-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Human MADCAM1 protein (Recombinant) (C-His) (STJP002437)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human MADCAM1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Immobilized Human MADCAM1, His Tag at 0.5 Mu g/ml (100 Mu l/Well) on the plate. Dose response curve for Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA.
Gene Symbol: MADCAM1
Gene ID: 8174
Uniprot ID: MADCA_HUMAN
Immunogen Region: Gln19-Gln317
Immunogen: Recombinant Human MADCAM1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln19-Gln317) of human MADCAM1 (Accession #NP_570116.2) fused with a 6×His tag at the C-terminus.
Post Translational Modifications The Ser/Thr-rich mucin-like domain may provide possible sites for O-glycosylation.
Function Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Protein Name Mucosal Addressin Cell Adhesion Molecule 1
Madcam-1
Hmadcam-1
Database Links Reactome: R-HSA-198933 Q13477-1
Reactome: R-HSA-216083 Q13477-1
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Mucosal Addressin Cell Adhesion Molecule 1 protein
Madcam-1 protein
Hmadcam-1 protein
MADCAM1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号