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  • 产品名称：Anti-ADNP antibody (843-1102) (STJ22524)

  • 产品型号：STJ22524
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ADNP antibody (843-1102) (STJ22524)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ADNP (843-1102) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADNP
Gene ID: 23394
Uniprot ID: ADNP_HUMAN
Immunogen Region: 843-1102
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 843-1102 of human ADNP (NP_056154.1).
Immunogen Sequence: EWLFENHDEKDSRVNASKTA DKKLNLGKEDDSSSDSFENL EEESNESGSPFDPVFEVEPK ISNDNPEEHVLKVIPEDASE SEEKLDQKEDGSKYETIHLT EEPTKLMHNASDSEVDQDDV VEWKDGASPSESGPGSQQVS DFEDNTCEMKPGTWSDESSQ SEDARSSKPAAKKKATMQGD REQLKWKNSSYGKVEGFWSK DQSQWKNASENDERLSNPQI EWQNSTIDSEDGEQFDNMT
Tissue Specificity Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
Function May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation.
Protein Name Activity-Dependent Neuroprotector Homeobox Protein
Activity-Dependent Neuroprotective Protein
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Activity-Dependent Neuroprotector Homeobox Protein antibody
Anti-Activity-Dependent Neuroprotective Protein antibody
Anti-ADNP antibody
Anti-ADNP1 antibody
Anti-KIAA0784 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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