产品详情
简单介绍:
Human Mesothelin/MSLN protein (Recombinant) (C-hFc & Avi) {Biotin} (STJP002186)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Mesothelin/MSLN-C-hFc & Avi protein was developed from hek293 cells and has a target region of C-hFc & Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MSLN |
Gene ID: | 10232 |
Uniprot ID: | MSLN_HUMAN |
Immunogen Region: | Glu296-Gly580 |
Immunogen: | Biotinylated Recombinant Human Mesothelin/MSLN Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Glu296-Gly580) of Human MSLN fused with a hFc tag and Avi tag at the C-terminal. |
Post Translational Modifications | Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin. |
Function | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. |
Protein Name | Mesothelin Cak1 Antigen Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor Mpf - Mesothelin - Cleaved Form |
Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Golgi Apparatus Megakaryocyte-Potentiating Factor: Secreted Isoform 3: Secreted |
Alternative Protein Names | Mesothelin protein Cak1 Antigen protein Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor protein Mpf - Mesothelin - Cleaved Form protein MSLN protein MPF protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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