产品详情
简单介绍:
Human MMP-9 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002182)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human MMP-9-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MMP9 |
Gene ID: | 4318 |
Uniprot ID: | MMP9_HUMAN |
Immunogen Region: | Ala20-Asp707 |
Immunogen: | Biotinylated Recombinant Human MMP9 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala20-Asp707) of Human MMP9 fused with a His and Avi tag at the C-terminal. |
Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
Protein Name | Matrix Metalloproteinase-9 Mmp-9 92 Kda Gelatinase 92 Kda Type Iv Collagenase Gelatinase B Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
Database Links | Reactome: R-HSA-1433557 Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 Reactome: R-HSA-2022090 Reactome: R-HSA-3928665 Reactome: R-HSA-6785807 Reactome: R-HSA-6798695 Reactome: R-HSA-9009391 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
Alternative Protein Names | Matrix Metalloproteinase-9 protein Mmp-9 protein 92 Kda Gelatinase protein 92 Kda Type Iv Collagenase protein Gelatinase B protein Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 protein MMP9 protein CLG4B protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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