产品详情
简单介绍:
Human MYDGF protein (Recombinant) (C-His) (STJP001958)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human MYDGF-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MYDGF |
Gene ID: | 56005 |
Uniprot ID: | MYDGF_HUMAN |
Immunogen Region: | Val32-Leu173 |
Immunogen: | Recombinant Human MYDGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val32-Leu173) of human MYDGF (Accession #NP_061980.1) fused with a 6×His tag at the C-terminus. |
Function | Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis. |
Protein Name | Myeloid-Derived Growth Factor Mydgf |
Database Links | Reactome: R-HSA-381038 |
Cellular Localisation | Secreted Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum Golgi Apparatus The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum |
Alternative Protein Names | Myeloid-Derived Growth Factor protein Mydgf protein MYDGF protein C19orf10 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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