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  • 产品名称：MAPK4 Blocking Peptide for STJ501706 peptide (STJ505444)

  • 产品型号：STJ505444-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
MAPK4 Blocking Peptide for STJ501706 peptide (STJ505444)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: MAPK4 Blocking Peptide for STJ501706 is synthetically produced from the 500-550 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MAPK4
Gene ID: 5596
Uniprot ID: MK04_HUMAN
Immunogen Region: 500-550
Specificity: This blocking peptide is recommended for use in combination with MAPK4 antibody, STJ501706
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human Mitogen-activated protein kinase 4.
Tissue Specificity High expression in heart and brain.
Post Translational Modifications Phosphorylated at Ser-186 by PAK1, PAK2 and PAK3 resulting in catalytic activation. Phosphorylated by MAPKAPK5 at other sites.
Function Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
Peptide Name Mitogen-Activated Protein Kinase 4
Map Kinase 4
Mapk 4
Extracellular Signal-Regulated Kinase 4
Erk-4
Map Kinase Isoform P63
P63-Mapk
Database Links Reactome: R-HSA-5687128
Cellular Localisation Cytoplasm
Nucleus
Translocates To The Cytoplasm Following Interaction With Mapkapk5
Alternative Peptide Names Mitogen-Activated Protein Kinase 4 protein
Map Kinase 4 protein
Mapk 4 protein
Extracellular Signal-Regulated Kinase 4 protein
Erk-4 protein
Map Kinase Isoform P63 protein
P63-Mapk protein
MAPK4 protein
ERK4 protein
PRKM4 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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