产品详情
简单介绍:
human Olfactomedin-4/OLFM4 protein (Recombinant) (C-6His) (STJP001934)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-human Olfactomedin-4/OLFM4-C-6His protein was developed from hek293 cells and has a target region of C-6His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | OLFM4 |
Gene ID: | 10562 |
Uniprot ID: | OLFM4_HUMAN |
Immunogen Region: | Asp21-Gln510 |
Immunogen: | Recombinant human Olfactomedin-4/OLFM4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp21-Gln510) of human Olfactomedin-4/OLFM4 (Accession #NP_006409.3) fused with a 6×His tag at the C-terminus |
Post Translational Modifications | N-glycosylated. |
Function | May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. |
Protein Name | Olfactomedin-4 Olm4 Antiapoptotic Protein Gw112 G-Csf-Stimulated Clone 1 Protein Hgc-1 Holfd |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted Extracellular Space Mitochondrion Subcellular Location Is Not Clearly Defined: Has Been Shown To Be Secreted But Also In The Mitochondrion Cytoplasm And Plasma Membrane And In The Nucleus |
Alternative Protein Names | Olfactomedin-4 protein Olm4 protein Antiapoptotic Protein Gw112 protein G-Csf-Stimulated Clone 1 Protein protein Hgc-1 protein Holfd protein OLFM4 protein GW112 protein UNQ362 protein PRO698 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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