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  • 产品名称：NHERF-1 Blocking Peptide for STJ506130 peptide (STJ505849)

  • 产品型号：STJ505849-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
NHERF-1 Blocking Peptide for STJ506130 peptide (STJ505849)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: NHERF-1 Blocking Peptide for STJ506130 is synthetically produced from the 255-305 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: NHERF1
Gene ID: 9368
Uniprot ID: NHRF1_HUMAN
Immunogen Region: 255-305
Specificity: This blocking peptide is recommended for use in combination with NHERF-1 antibody, STJ506130
Immunogen: Synthetic peptide corresponding to amino acids within region 255-305 on human (+) /H (+) exchange regulatory cofactor NHE-RF1.
Tissue Specificity Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.
Post Translational Modifications Phosphorylated on serine residues.
Function Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
Peptide Name Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf1
Nherf-1
Ezrin-Radixin-Moesin-Binding Phosphoprotein 50
Ebp50
Regulatory Cofactor Of Na(+/H(+ Exchanger
Sodium-Hydrogen Exchanger Regulatory Factor 1
Solute Carrier Family 9 Isoform A3 Regulatory Factor 1
Cellular Localisation Cytoplasm
Apical Cell Membrane
Endomembrane System
Peripheral Membrane Protein
Cell Projection
Filopodium
Ruffle
Microvillus
Translocates From The Cytoplasm To The Apical Cell Membrane In A Podxl-Dependent Manner
Colocalizes With Cftr At The Midpiece Of Sperm Tail
Colocalizes With Actin In Microvilli-Rich Apical Regions Of The Syncytiotrophoblast
Found In Microvilli
Ruffling Membrane And Filopodia Of Hela Cells
Present In Lipid Rafts Of T-Cells
Alternative Peptide Names Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf1 protein
Nherf-1 protein
Ezrin-Radixin-Moesin-Binding Phosphoprotein 50 protein
Ebp50 protein
Regulatory Cofactor Of Na(+/H(+ Exchanger protein
Sodium-Hydrogen Exchanger Regulatory Factor 1 protein
Solute Carrier Family 9 Isoform A3 Regulatory Factor 1 protein
NHERF1 protein
NHERF protein
SLC9A3R1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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