产品详情
简单介绍:
Human Placenta growth factor/PLGF-131 protein (Recombinant) (C-hFc) (STJP002466)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Placenta growth factor/PLGF-131-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PGF |
Gene ID: | 5228 |
Uniprot ID: | PLGF_HUMAN |
Immunogen Region: | Leu19-Arg149 |
Immunogen: | Recombinant human PIG-F Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu19-Arg149) fused with a hFc tag at the C-terminus. |
Post Translational Modifications | N-glycosylated. |
Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. |
Protein Name | Placenta Growth Factor Plgf |
Database Links | Reactome: R-HSA-194313 Reactome: R-HSA-195399 |
Cellular Localisation | Secreted The Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin |
Alternative Protein Names | Placenta Growth Factor protein Plgf protein PGF protein PGFL protein PLGF protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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