产品详情
查看大图

  • 产品名称：NM23A Blocking Peptide peptide (STJ504403)

  • 产品型号：STJ504403-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
NM23A Blocking Peptide peptide (STJ504403)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: NM23A Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: NME1
Gene ID: 4830
Uniprot ID: NDKA_HUMAN
Immunogen Region: 1-100
Immunogen: Synthetic peptide taken within amino acid region 1-100 on human NDKA protein.
Tissue Specificity Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation.
Function Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
Peptide Name Nucleoside Diphosphate Kinase A
Ndk A
Ndp Kinase A
Granzyme A-Activated Dnase
Gaad
Metastasis Inhibition Factor Nm23
Nm23-H1
Tumor Metastatic Process-Associated Protein
Database Links Reactome: R-HSA-499943
Reactome: R-HSA-9748787
Reactome: R-HSA-9755088
Cellular Localisation Cytoplasm
Nucleus
Cell-Cycle Dependent Nuclear Localization Which Can Be Induced By Interaction With Epstein-Barr Viral Proteins Or By Degradation Of The Set Complex By Gzma
Alternative Peptide Names Nucleoside Diphosphate Kinase A protein
Ndk A protein
Ndp Kinase A protein
Granzyme A-Activated Dnase protein
Gaad protein
Metastasis Inhibition Factor Nm23 protein
Nm23-H1 protein
Tumor Metastatic Process-Associated Protein protein
NME1 protein
NDPKA protein
NM23 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号