产品详情
查看大图

  • 产品名称：NTH1 Blocking Peptide peptide (STJ504429)

  • 产品型号：STJ504429-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
NTH1 Blocking Peptide peptide (STJ504429)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: NTH1 Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: NTHL1
Gene ID: 4913
Uniprot ID: NTH_HUMAN
Immunogen Region: 1-100
Immunogen: N-epitope synthetic peptide taken within amino acid region 1-100 on human NTHL1 protein.
Tissue Specificity Widely expressed with highest levels in heart and lowest levels in lung and liver.
Post Translational Modifications Ubiquitinated by TRIM26.leading to proteasomal degradation.
Function Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
Peptide Name Endonuclease Iii-Like Protein 1
Hnth1
Bifunctional Dna N-Glycosylase/Dna-(Apurinic Or Apyrimidinic Site Lyase
Dna Glycosylase/Ap Lyase
Database Links Reactome: R-HSA-110328
Reactome: R-HSA-110329
Reactome: R-HSA-110357
Reactome: R-HSA-9630221
Reactome: R-HSA-9630222
Cellular Localisation Nucleus
Mitochondrion
Alternative Peptide Names Endonuclease Iii-Like Protein 1 protein
Hnth1 protein
Bifunctional Dna N-Glycosylase/Dna-(Apurinic Or Apyrimidinic Site Lyase protein
Dna Glycosylase/Ap Lyase protein
NTHL1 protein
NTH1 protein
OCTS3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号