产品详情
简单介绍:
Nurr1 Blocking Peptide peptide (STJ504433)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Nurr1 Blocking Peptide is synthetically produced from the 566-591 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | NR4A2 |
Gene ID: | 4929 |
Uniprot ID: | NR4A2_HUMAN |
Immunogen Region: | 566-591 |
Immunogen: | Synthetic peptide corresponding to amino acid region 566-591. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker. Sequence: CTQGLQRIFYLKLEDLVP |
Tissue Specificity | Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue. |
Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
Peptide Name | Nuclear Receptor Subfamily 4 Group A Member 2 Immediate-Early Response Protein Not Orphan Nuclear Receptor Nurr1 Transcriptionally-Inducible Nuclear Receptor |
Database Links | Reactome: R-HSA-383280 Reactome: R-HSA-4090294 |
Cellular Localisation | Cytoplasm Nucleus Mostly Nuclear Oxidative Stress Promotes Cytoplasmic Localization |
Alternative Peptide Names | Nuclear Receptor Subfamily 4 Group A Member 2 protein Immediate-Early Response Protein Not protein Orphan Nuclear Receptor Nurr1 protein Transcriptionally-Inducible Nuclear Receptor protein NR4A2 protein NOT protein NURR1 protein TINUR protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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