产品详情
  • 产品名称:Anti-AMOTL1 antibody (810-900) (STJ11100083)

  • 产品型号:STJ11100083
  • 产品厂商:ST john's laboratory
  • 产品文档:
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简单介绍:
Anti-AMOTL1 antibody (810-900) (STJ11100083)
详情介绍:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AMOTL1 (810-900) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AMOTL1
Gene ID: 154810
Uniprot ID: AMOL1_HUMAN
Immunogen Region: 810-900
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 810-900 of human AMOTL1 (NP_570899.1).
Immunogen Sequence: LTSSQLAEEKKEEKTWKGSI GLLLGKEHHEHASAPLLPPP PTSALSSIASTTAASSAHAK TGSKDSSTQTDKSAELFWPS MASLPSRGRLS
Post Translational Modifications Polyubiquitinated by NEDD4, leading to proteasomal degradation.
Function Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Protein Name Angiomotin-Like Protein 1
Database Links Reactome: R-HSA-2028269
Cellular Localisation Cell Junction
Tight Junction
Alternative Antibody Names Anti-Angiomotin-Like Protein 1 antibody
Anti-AMOTL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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