产品详情
简单介绍:
Anti-AMOTL1 antibody (810-900) (STJ11100083)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-AMOTL1 (810-900) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | AMOTL1 |
Gene ID: | 154810 |
Uniprot ID: | AMOL1_HUMAN |
Immunogen Region: | 810-900 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 810-900 of human AMOTL1 (NP_570899.1). |
Immunogen Sequence: | LTSSQLAEEKKEEKTWKGSI GLLLGKEHHEHASAPLLPPP PTSALSSIASTTAASSAHAK TGSKDSSTQTDKSAELFWPS MASLPSRGRLS |
Post Translational Modifications | Polyubiquitinated by NEDD4, leading to proteasomal degradation. |
Function | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
Protein Name | Angiomotin-Like Protein 1 |
Database Links | Reactome: R-HSA-2028269 |
Cellular Localisation | Cell Junction Tight Junction |
Alternative Antibody Names | Anti-Angiomotin-Like Protein 1 antibody Anti-AMOTL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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