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  • 产品名称：Anti-AGRP/Agouti-related protein antibody (C-Term) (STJ70688)

  • 产品型号：STJ70688-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AGRP/Agouti-related protein antibody (C-Term) (STJ70688)
详情介绍：
Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Dog/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-AGRP/Agouti-related protein (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-0.05-0.1µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: AGRP
Gene ID: 181
Uniprot ID: AGRP_HUMAN
Immunogen Region: C-Term
Accession Number: NP_001129.1; NP_015531.1
Specificity: This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531)
Immunogen Sequence: CRKLGTAMNPCSRT
Function Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Protein Name Agouti-Related Protein
Database Links Reactome: R-HSA-9615017
Cellular Localisation Secreted
Golgi Apparatus Lumen
Alternative Antibody Names Anti-Agouti-Related Protein antibody
Anti-AGRP antibody
Anti-AGRT antibody
Anti-ART antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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