Name: Human BCAR1 (Breast cancer anti-estrogen resistance protein 1) CLIA Kit (STJC0000965)
Brand: ST john's laboratory
SKU: STJC0000965

所在位置: 首页> 产品目录> S类> ST john's laboratory>

查看大图

产品名称：Human BCAR1 (Breast cancer anti-estrogen resistance protein 1) CLIA Kit (STJC0000965)
产品型号：STJC0000965
产品厂商：ST john's laboratory
产品文档：

你添加了1件商品查看购物车

简单介绍：

Human BCAR1 (Breast cancer anti-estrogen resistance protein 1) CLIA Kit (STJC0000965)

详情介绍：

Applications:	CLIA
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity:	18.75pg/mL
Detection Limit:	31.25~2000pg/mL
Short Description:	This human BCAR1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.

Storage Instruction:	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time:	3.5h
Detection:	Chemiluminescence

Gene Symbol:	BCAR1
Gene ID:	9564
Uniprot ID:	BCAR1_HUMAN
Specificity:	This kit recognizes Human BCAR1 in samples. No significant cross-reactivity or interference between Human BCAR1 and analogues was observed.
Sample Type:	Serum, plasma and other biological fluids

Tissue Specificity	Expressed in B-cells (at protein level). Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes.
Post Translational Modifications	PTK2/FAK1 activation mediates phosphorylation at the YDYVHL motif.phosphorylation is most likely catalyzed by SRC family members. SRC-family kinases are recruited to the phosphorylated sites and can phosphorylate other tyrosine residues. Tyrosine phosphorylation is triggered by integrin-mediated adhesion of cells to the extracellular matrix. Dephosphorylated by PTPN14 at Tyr-128. Phosphorylated by SRC kinase in a EDN1- and PTK2B-mediated manner.phosphorylation strengthens its interaction with BCAR3 as part of the PTK2B/BCAR1/BCAR3/RAP1 signaling pathway.
Function	Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration and cell branching. Involved in the BCAR3-mediated inhibition of TGFB signaling.
Protein Name	Breast Cancer Anti-Estrogen Resistance Protein 1 Crk-Associated Substrate Cas Scaffolding Protein Family Member 1 P130cas
Database Links	Reactome: R-HSA-186763 Reactome: R-HSA-372708 Reactome: R-HSA-4420097 Reactome: R-HSA-8849471
Cellular Localisation	Cell Junction Focal Adhesion Cytoplasm Cell Projection Axon Unphosphorylated Form Localizes In The Cytoplasm Localizes To Focal Adhesion Sites Following Integrin Engagement
Alternative CLIA Names	Breast Cancer Anti-Estrogen Resistance Protein 1 CLIA kit Crk-Associated Substrate CLIA kit Cas Scaffolding Protein Family Member 1 CLIA kit P130cas CLIA kit BCAR1 CLIA kit CAS CLIA kit CASS1 CLIA kit CRKAS CLIA kit
Specificity	This kit recognizes Human BCAR1 in samples. No significant cross-reactivity or interference between Human BCAR1 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item Specifications Storage

Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type Range (%) Average Recovery (%)

Serum(n=8)	93-107	101
EDTA plasma(n=8)	99-113	106
Cell culture media(n=8)	95-106	101

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision

Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	95.90	284.94	882.64	90.87	270.63	890.03
Standard deviation	8.21	23.19	94.80	10.87	28.04	97.90
CV (%)	8.56	8.14	10.74	11.96	10.36	11.00

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

电话：

您的需求：

产品名称：Human BCAR1 (Breast cancer anti-estrogen resistance protein 1) CLIA Kit (STJC0000965)