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  • 产品名称：Human Sclerostin protein (Recombinant) {Biotin} (STJP000216)

  • 产品型号：STJP000216
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human Sclerostin protein (Recombinant) {Biotin} (STJP000216)
详情介绍：
Host: HEK293
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Sclerostin-protein was developed from hek293. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol: SOST
Gene ID: 50964
Uniprot ID: SOST_HUMAN
Immunogen Region: GLN24-TYR213
Immunogen: Optimized DNA sequence encoding extracellular domain of Human Sclerostin (GLN24-TYR213) including a N-terminal His tag was expressed in HEK293 cells. Recombinant Sclerostin was further labled by Biotin for detection by avidin conjugated secondary pro
Tissue Specificity Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level).
Function Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Protein Name Sclerostin
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-3772470
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Sclerostin protein
SOST protein
UNQ2976 protein
PRO7455 protein
PRO7476 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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