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  • 产品名称：Human SELP/P-Selectin/CD62P protein (Recombinant) (C-hFc&His) (STJP001390)

  • 产品型号：STJP001390
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human SELP/P-Selectin/CD62P protein (Recombinant) (C-hFc&His) (STJP001390)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SELP/P-Selectin/CD62P-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity: Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When 5 x 10E4 cells/well are added to Human SELP coated plates (10 Mu g/mL with 100 Mu L/well) , > 80% cells will adhere after 1 hour
Gene Symbol: SELP
Gene ID: 6403
Uniprot ID: LYAM3_HUMAN
Immunogen: Recombinant Human SELP/P-Selectin/CD62P Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp42-Ala771) of human P-Selectin/CD62P (Accession #NP_002996.2) fused with a Fc, 6×His tag at the C-terminu
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Protein Name P-Selectin
Cd62 Antigen-Like Family Member P
Granule Membrane Protein 140
Gmp-140
Leukocyte-Endothelial Cell Adhesion Molecule 3
Lecam3
Platelet Activation Dependent Granule-External Membrane Protein
Padgem
Cd Antigen Cd62p
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names P-Selectin protein
Cd62 Antigen-Like Family Member P protein
Granule Membrane Protein 140 protein
Gmp-140 protein
Leukocyte-Endothelial Cell Adhesion Molecule 3 protein
Lecam3 protein
Platelet Activation Dependent Granule-External Membrane Protein protein
Padgem protein
Cd Antigen Cd62p protein
SELP protein
GMRP protein
GRMP protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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