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  • 产品名称：Anti-ANKFY1 antibody (922-972 aa) (STJ197960)

  • 产品型号：STJ197960
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ANKFY1 antibody (922-972 aa) (STJ197960)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Rabankyrin-5 (922-972 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANKFY1
Gene ID: 51479
Uniprot ID: ANFY1_HUMAN
Immunogen Region: 922-972 aa
Specificity: This antibody detects endogenous levels of human ANFY1
Immunogen: Synthesized peptide derived from the human ANFY1 at the amino acid range 922-972
Function Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis.the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport.
Protein Name Rabankyrin-5
Rank-5
Ankyrin Repeat And Fyve Domain-Containing Protein 1
Ankyrin Repeats Hooked To A Zinc Finger Motif
Database Links Reactome: R-HSA-9013405
Cellular Localisation Cytoplasm
Endosome Membrane
Peripheral Membrane Protein
Early Endosome
Also Associated With Endosomal Membranes
Localizes To Macropinosomes
Alternative Antibody Names Anti-Rabankyrin-5 antibody
Anti-Rank-5 antibody
Anti-Ankyrin Repeat And Fyve Domain-Containing Protein 1 antibody
Anti-Ankyrin Repeats Hooked To A Zinc Finger Motif antibody
Anti-ANKFY1 antibody
Anti-ANKHZN antibody
Anti-KIAA1255 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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