产品详情
查看大图

  • 产品名称：Anti-AICDA antibody (STJ11103856)

  • 产品型号：STJ11103856
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-AICDA antibody (STJ11103856)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AICDA is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Aicda
Gene ID: 11628
Uniprot ID: AICDA_MOUSE
Immunogen: A synthetic peptide of mouse AICDA
Tissue Specificity Expressed in germinal center B-cells (at protein level).
Post Translational Modifications Ser-38 is the major site whereas Thr-27 is the minor site of phosphorylation. Phosphorylation regulates its class-switch recombination activity. Probably monoubiquitinated on several residues by RNF126.
Function Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Protein Name Single-Stranded Dna Cytosine Deaminase
Activation-Induced Cytidine Deaminase
Aid
Cytidine Aminohydrolase
Cellular Localisation Nucleus
Cytoplasm
Predominantly Cytoplasmic
In The Presence Of Mcm3ap/Ganp
Relocalizes To The Nucleus
Alternative Antibody Names Anti-Single-Stranded Dna Cytosine Deaminase antibody
Anti-Activation-Induced Cytidine Deaminase antibody
Anti-Aid antibody
Anti-Cytidine Aminohydrolase antibody
Anti-Aicda antibody
Anti-Aid antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号