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  • 产品名称：PAR1 Blocking Peptide for STJ502112 peptide (STJ504529)

  • 产品型号：STJ504529-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
PAR1 Blocking Peptide for STJ502112 peptide (STJ504529)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PAR1 Blocking Peptide for STJ502112 is synthetically produced from the 390-440 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: F2r
Gene ID: 14062
Uniprot ID: PAR1_MOUSE
Immunogen Region: 390-440
Specificity: This blocking peptide is recommended for use in combination with PAR1 antibody, STJ502112
Immunogen: Synthetic peptide taken within amino acid region 390-440 on mouse PAR1 protein.
Post Translational Modifications Proteolytic cleavage by thrombin generates a new N-terminus that functions as a tethered ligand. Also proteolytically cleaved by cathepsin CTSG. Phosphorylated in the C-terminal tail.probably mediating desensitization prior to the uncoupling and internalization of the receptor.
Function High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Peptide Name Proteinase-Activated Receptor 1
Par-1
Thrombin Receptor
Database Links Reactome: R-MMU-140875
Reactome: -MMU-375276
Reactome: -MMU-416476
Reactome: -MMU-456926
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Proteinase-Activated Receptor 1 protein
Par-1 protein
Thrombin Receptor protein
F2r protein
Cf2r protein
Par1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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