产品详情
简单介绍:
Human BMPR1B (Bone Morphogenetic Protein Receptor 1B) Sandwich ELISA Kit (STJE0007532)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.134ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This BMPR1B Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | BMPR1B |
Gene ID: | 658 |
Uniprot ID: | BMR1B_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Autophosphorylated. |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
Protein Name | Bone Morphogenetic Protein Receptor Type-1b Bmp Type-1b Receptor Bmpr-1b Cd Antigen Cdw293 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative ELISA Names | Bone Morphogenetic Protein Receptor Type-1b ELISA kit Bmp Type-1b Receptor ELISA kit Bmpr-1b ELISA kit Cd Antigen Cdw293 ELISA kit BMPR1B ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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