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  • 产品名称：Human SPAM1 (PH-20) protein (Recombinant) (STJP000531)

  • 产品型号：STJP000531
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human SPAM1 (PH-20) protein (Recombinant) (STJP000531)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SPAM1 (PH-20)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol: SPAM1
Gene ID: 6677
Uniprot ID: HYALP_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of human SPAM1 (PH20) (LEU36-TYR482 ) including a C-terminal His tag was expressed in HEK293 cells. NA
Tissue Specificity Testis.
Post Translational Modifications N-glycosylated.
Function Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Protein Name Hyaluronidase Ph-20
Hyal-Ph20
Hyaluronoglucosaminidase Ph-20
Sperm Adhesion Molecule 1
Sperm Surface Protein Ph-20
Database Links Reactome: R-HSA-2534343
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Hyaluronidase Ph-20 protein
Hyal-Ph20 protein
Hyaluronoglucosaminidase Ph-20 protein
Sperm Adhesion Molecule 1 protein
Sperm Surface Protein Ph-20 protein
SPAM1 protein
HYAL3 protein
PH20 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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