产品详情
查看大图

  • 产品名称：Human Sulfotransferase 1A1/SULT1A1 protein (Recombinant) (C-His) (STJP000812)

  • 产品型号：STJP000812
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Human Sulfotransferase 1A1/SULT1A1 protein (Recombinant) (C-His) (STJP000812)
详情介绍：
Host: E. coli
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Sulfotransferase 1A1/SULT1A1-C-His protein was developed from e. coli and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 20mM TRIS, 150mM NaCl, pH 8.0. Contact us for customized product form or formulation.
Gene Symbol: SULT1A1
Gene ID: 6817
Uniprot ID: ST1A1_HUMAN
Immunogen: Recombinant Human Sulfotransferase 1A1/SULT1A1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu295) of human SULT1A1 (Accession #NP_001046.2) fused with a 6×His tag at the C-terminus.
Tissue Specificity Liver, lung, adrenal, brain, platelets and skin.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a wide variety of acceptor molecules bearing a hydroxyl or an amine groupe. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Displays broad substrate specificity for small phenolic compounds. Plays an important role in the sulfonation of endogenous molecules such as steroid hormones and 3,3'-diiodothyronin. Mediates the sulfate conjugation of a variety of xenobiotics, including the drugs acetaminophen and minoxidil. Mediates also the metabolic activation of carcinogenic N-hydroxyarylamines leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis. May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system.
Protein Name Sulfotransferase 1a1
St1a1
Aryl Sulfotransferase 1
Hast1/Hast2
Phenol Sulfotransferase 1
Phenol-Sulfating Phenol Sulfotransferase 1
P-Pst 1
St1a3
Thermostable Phenol Sulfotransferase
Ts-Pst
Database Links Reactome: R-HSA-156584
Reactome: R-HSA-9753281
Cellular Localisation Cytoplasm
Alternative Protein Names Sulfotransferase 1a1 protein
St1a1 protein
Aryl Sulfotransferase 1 protein
Hast1/Hast2 protein
Phenol Sulfotransferase 1 protein
Phenol-Sulfating Phenol Sulfotransferase 1 protein
P-Pst 1 protein
St1a3 protein
Thermostable Phenol Sulfotransferase protein
Ts-Pst protein
SULT1A1 protein
STP protein
STP1 protein
OK protein
SW-cl.88 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号