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  • 产品名称：PDE11A Blocking Peptide peptide (Phospho) (S117/S124) (STJ504774)

  • 产品型号：STJ504774-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
PDE11A Blocking Peptide peptide (Phospho) (S117/S124) (STJ504774)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Phospho-PDE11A Blocking Peptide is synthetically produced from the 100-150 sequence about the S117/S124 and is suitable for use in western blot applications.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE11A
Gene ID: 50940
Uniprot ID: PDE11_HUMAN
Immunogen Region: 100-150
Immunogen: Synthetic peptide taken within amino acid region 100-150 on PDE11A protein. Phosphorylated Ser 117 & 124.
Tissue Specificity Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil (Cialis) is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed in adrenal cortex.
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
Peptide Name Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a
Camp And Cgmp Phosphodiesterase 11a
Database Links Reactome: R-HSA-418457
Reactome: R-HSA-418555
Cellular Localisation Cytoplasm
Cytosol
Alternative Peptide Names Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a protein
Camp And Cgmp Phosphodiesterase 11a protein
PDE11A protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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