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  • 产品名称：Anti-APBA1 antibody (240-390) (STJ11100529)

  • 产品型号：STJ11100529
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-APBA1 antibody (240-390) (STJ11100529)
详情介绍：
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-APBA1 (240-390) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APBA1
Gene ID: 320
Uniprot ID: APBA1_HUMAN
Immunogen Region: 240-390
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human APBA1 (NP_001154.2).
Immunogen Sequence: ERSDGESDSPEKEAEFAPYP RMDSYEQEEDIDQIVAEVKQ SMSSQSLDKAAEDMPEAEQD LERPPTPAGGRPDSPGLQAP AGQQRAVGPAGGGEAGQRYS KEKRDAISLAIKDIKEAIEE VKTRTIRSPYTPDEPKEPIW VMRQDISPTRD
Tissue Specificity Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen.
Function Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
Protein Name Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1
Adapter Protein X11alpha
Neuron-Specific X11 Protein
Neuronal Munc18-1-Interacting Protein 1
Mint-1
Database Links Reactome: R-HSA-212676
Reactome: R-HSA-6794361
Reactome: R-HSA-9609736
Cellular Localisation Cytoplasm
Perinuclear Region
Nucleus
Only About 5% Of The Protein Is Located In The Nucleus
Isoform 2: Golgi Apparatus
Alternative Antibody Names Anti-Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1 antibody
Anti-Adapter Protein X11alpha antibody
Anti-Neuron-Specific X11 Protein antibody
Anti-Neuronal Munc18-1-Interacting Protein 1 antibody
Anti-Mint-1 antibody
Anti-APBA1 antibody
Anti-MINT1 antibody
Anti-X11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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