产品详情
简单介绍:
Human CACNa1D (Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit) Sandwich ELISA Kit (STJE0007635)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.121ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This CACNa1D Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | CACNA1D |
Gene ID: | 776 |
Uniprot ID: | CAC1D_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in pancreatic islets and in brain, where it has been seen in cerebral cortex, hippocampus, basal ganglia, habenula and thalamus. Expressed in the small cell lung carcinoma cell line SCC-9. No expression in skeletal muscle. |
Post Translational Modifications | |
Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. |
Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 |
Database Links | Reactome: R-HSA-400042 Reactome: R-HSA-419037 Reactome: R-HSA-422356 Reactome: R-HSA-9662360 |
Cellular Localisation | Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d ELISA kit Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 ELISA kit Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 ELISA kit CACNA1D ELISA kit CACH3 ELISA kit CACN4 ELISA kit CACNL1A2 ELISA kit CCHL1A2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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