产品详情
简单介绍:
Human TNFRSF25/DR3 protein (Recombinant) (C-hFc) (STJP002627)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human TNFRSF25/DR3-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TNFRSF25 |
Gene ID: | 8718 |
Uniprot ID: | TNR25_HUMAN |
Immunogen Region: | Met1-Gln199 |
Immunogen: | Recombinant Human TNFRSF25/DR3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Gln199) of human TNFRSF25/DR3 (Accession #Q93038) fused with a hFc tag at the C-terminus. |
Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25 Apo-3 Apoptosis-Inducing Receptor Air Apoptosis-Mediating Receptor Dr3 Apoptosis-Mediating Receptor Tramp Death Receptor 3 Lymphocyte-Associated Receptor Of Death Lard Protein Wsl Protein Wsl-1 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Cell Membrane Isoform 9: Cell Membrane Isoform 11: Cell Membrane Isoform 3: Secreted Isoform 4: Secreted Isoform 5: Secreted Isoform 6: Secreted Isoform 7: Secreted Isoform 8: Secreted Isoform 10: Secreted Isoform 12: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 25 protein Apo-3 protein Apoptosis-Inducing Receptor Air protein Apoptosis-Mediating Receptor Dr3 protein Apoptosis-Mediating Receptor Tramp protein Death Receptor 3 protein Lymphocyte-Associated Receptor Of Death protein Lard protein Protein Wsl protein Protein Wsl-1 protein TNFRSF25 protein APO3 protein DDR3 protein DR3 protein TNFRSF12 protein WSL protein WSL1 protein UNQ455 protein PRO779 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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