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  • 产品名称：Human TNFRSF5/CD40 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002115)

  • 产品型号：STJP002115-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human TNFRSF5/CD40 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002115)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TNFRSF5/CD40-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Immobilized Biotinylated Human CD40 at 1 Mu g/mL (100 Mu L/Well) on streptavidin precoated (0.2 Mu g/well) plate.Dose response curve for Human CD40Lwith the EC50 of 15 ng/mL determined by ELISA.
Gene Symbol: CD40
Gene ID: 958
Uniprot ID: TNR5_HUMAN
Immunogen Region: Glu21-Arg193
Immunogen: Biotinylated Recombinant Human CD40 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Glu21-Arg193) of Human CD40 fused with a His and a Avi tag at the C-terminal.
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 5 protein
B-Cell Surface Antigen Cd40 protein
Bp50 protein
Cd40l Receptor protein
Cdw40 protein
Cd Antigen Cd40 protein
CD40 protein
TNFRSF5 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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