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  • 产品名称：Anti-APOA5 antibody (207-366) (STJ22645)

  • 产品型号：STJ22645
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-APOA5 antibody (207-366) (STJ22645)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-APOA5 (207-366) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOA5
Gene ID: 116519
Uniprot ID: APOA5_HUMAN
Immunogen Region: 207-366
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 207-366 of human APOA5 (NP_443200.2).
Immunogen Sequence: QELHRSVAPHAPASPARLSR CVQVLSRKLTLKAKALHARI QQNLDQLREELSRAFAGTGT EEGAGPDPQMLSEEVRQRLQ AFRQDTYLQIAAFTRAIDQE TEEVQQQLAPPPPGHSAFAP EFQQTDSGKVLSKLQARLDD LWEDITHSLHDQGHSHLGDP
Tissue Specificity Liver and plasma.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin.
Protein Name Apolipoprotein A-V
Apo-Av
Apoa-V
Apolipoprotein A5
Regeneration-Associated Protein 3
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-8963889
Reactome: R-HSA-8963901
Cellular Localisation Secreted
Early Endosome
Late Endosome
Golgi Apparatus
Trans-Golgi Network
In The Presence Of Sorl1
Internalized To Early Endosomes
Sorted In A Retrograde Fashion To Late Endosomes
From Which A Portion Is Sent To Lysosomes And Degradation
Another Portion Is Sorted To The Trans-Golgi Network
Alternative Antibody Names Anti-Apolipoprotein A-V antibody
Anti-Apo-Av antibody
Anti-Apoa-V antibody
Anti-Apolipoprotein A5 antibody
Anti-Regeneration-Associated Protein 3 antibody
Anti-APOA5 antibody
Anti-RAP3 antibody
Anti-UNQ411 antibody
Anti-PRO773 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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