产品详情
简单介绍:
Anti-APOA5 antibody (30-110 aa) (STJ91634)
详情介绍:
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Apolipoprotein A-V (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOA5 |
| Gene ID: | 116519 |
| Uniprot ID: | APOA5_HUMAN |
| Immunogen Region: | 30-110 aa |
| Specificity: | ApoA-V Polyclonal Antibody detects endogenous levels of ApoA-V protein. |
| Immunogen: | Synthesized peptide derived from ApoA-V at the amino acid range 30-110 |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin. |
| Protein Name | Apolipoprotein A-V Apo-Av Apoa-V Apolipoprotein A5 Regeneration-Associated Protein 3 |
| Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 Reactome: R-HSA-8963889 Reactome: R-HSA-8963901 |
| Cellular Localisation | Secreted Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network In The Presence Of Sorl1 Internalized To Early Endosomes Sorted In A Retrograde Fashion To Late Endosomes From Which A Portion Is Sent To Lysosomes And Degradation Another Portion Is Sorted To The Trans-Golgi Network |
| Alternative Antibody Names | Anti-Apolipoprotein A-V antibody Anti-Apo-Av antibody Anti-Apoa-V antibody Anti-Apolipoprotein A5 antibody Anti-Regeneration-Associated Protein 3 antibody Anti-APOA5 antibody Anti-RAP3 antibody Anti-UNQ411 antibody Anti-PRO773 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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