产品详情
简单介绍:
Anti-APOA5 antibody [4H8H8E2 (c)] (STJ97837)
详情介绍:
Host: | Mouse |
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Apolipoprotein A-V is suitable for use in ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 4H8H8E2 (c) |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide. |
Purification: | Affinity purification |
Concentration: | 1 mg/mL |
Dilution Range: | ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | APOA5 |
Gene ID: | 116519 |
Uniprot ID: | APOA5_HUMAN |
Specificity: | ApoA-V (bd) Monoclonal Antibody detects endogenous levels of ApoA-V (bd) protein. |
Immunogen: | Purified recombinant fragment of human ApoA-V expressed in E. Coli. |
Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
Function | Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin. |
Protein Name | Apolipoprotein A-V Apo-Av Apoa-V Apolipoprotein A5 Regeneration-Associated Protein 3 |
Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 Reactome: R-HSA-8963889 Reactome: R-HSA-8963901 |
Cellular Localisation | Secreted Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network In The Presence Of Sorl1 Internalized To Early Endosomes Sorted In A Retrograde Fashion To Late Endosomes From Which A Portion Is Sent To Lysosomes And Degradation Another Portion Is Sorted To The Trans-Golgi Network |
Alternative Antibody Names | Anti-Apolipoprotein A-V antibody Anti-Apo-Av antibody Anti-Apoa-V antibody Anti-Apolipoprotein A5 antibody Anti-Regeneration-Associated Protein 3 antibody Anti-APOA5 antibody Anti-RAP3 antibody Anti-UNQ411 antibody Anti-PRO773 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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