产品详情
简单介绍:
Human CAPZb (Capping Protein Muscle Z Line Beta) Sandwich ELISA Kit (STJE0007678)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.052ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This CAPZb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | CAPZB |
Gene ID: | 832 |
Uniprot ID: | CAPZB_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules. |
Protein Name | F-Actin-Capping Protein Subunit Beta Capz Beta |
Database Links | Reactome: R-HSA-2132295 Reactome: R-HSA-3371497 Reactome: R-HSA-6807878 Reactome: R-HSA-6811436 Reactome: R-HSA-9013405 Reactome: R-HSA-9035034 Reactome: R-HSA-9662360 Reactome: R-HSA-983231 |
Cellular Localisation | Cytoplasm Cytoskeleton Myofibril Sarcomere |
Alternative ELISA Names | F-Actin-Capping Protein Subunit Beta ELISA kit Capz Beta ELISA kit CAPZB ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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