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  • 产品名称：Human uPAR protein (Recombinant) (STJP001869)

  • 产品型号：STJP001869
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human uPAR protein (Recombinant) (STJP001869)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human uPAR-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity: The activity was tested by the ability of immobilized uPAR to bind recombinant human uPA within a linear range of 20-500 ng/ml in ELISA NA
Gene Symbol: PLAUR
Gene ID: 5329
Uniprot ID: UPAR_HUMAN
Immunogen Region: LEU23-ARG303
Immunogen: Optimized DNA sequence encoding Urokinase-type plasminogen activator receptor (LEU23-ARG303) including a C-terminal His tag was expressed in HEK293 cells. NA
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Protein Names Urokinase Plasminogen Activator Surface Receptor protein
U-Par protein
Upar protein
Monocyte Activation Antigen Mo3 protein
Cd Antigen Cd87 protein
PLAUR protein
MO3 protein
UPAR protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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