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  • 产品名称：Anti-ACVR1C antibody (201-250 aa) (STJ91472)

  • 产品型号：STJ91472
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ACVR1C antibody (201-250 aa) (STJ91472)
详情介绍：
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Activin receptor type-1C (201-250 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACVR1C
Gene ID: 130399
Uniprot ID: ACV1C_HUMAN
Immunogen Region: 201-250 aa
Specificity: ACTR-IC Polyclonal Antibody detects endogenous levels of ACTR-IC protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ACTR-1C at the amino acid range 201-250
Function Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Protein Name Activin Receptor Type-1c
Activin Receptor Type Ic
Actr-Ic
Activin Receptor-Like Kinase 7
Alk-7
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Activin Receptor Type-1c antibody
Anti-Activin Receptor Type Ic antibody
Anti-Actr-Ic antibody
Anti-Activin Receptor-Like Kinase 7 antibody
Anti-Alk-7 antibody
Anti-ACVR1C antibody
Anti-ALK7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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