产品详情
简单介绍:
GAN Positive Control for STJ507836 peptide (STJ507838)
详情介绍:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | GAN Positive Control for STJ507836 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | GAN |
Gene ID: | 8139 |
Uniprot ID: | GAN_HUMAN |
Specificity: | This is positive control is recommended for use in combination with GAN antibody STJ507836. |
Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. |
Function | Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. |
Peptide Name | Gigaxonin Kelch-Like Protein 16 |
Database Links | Reactome: R-HSA-8951664 Reactome: R-HSA-983168 |
Cellular Localisation | Cytoplasm Cytoskeleton |
Alternative Peptide Names | Gigaxonin protein Kelch-Like Protein 16 protein GAN protein GAN1 protein KLHL16 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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