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  • 产品名称：Human IFN-lambda 1/IL-29 protein (Recombinant) (C-His) (STJP001077)

  • 产品型号：STJP001077
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human IFN-lambda 1/IL-29 protein (Recombinant) (C-His) (STJP001077)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human IFN-lambda 1/IL-29-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: Please contact us for more information.
Gene Symbol: IFNL1
Gene ID: 282618
Uniprot ID: IFNL1_HUMAN
Immunogen: Recombinant Human IFN-lambda 1/IL-29 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gly20-Thr200) of human IL-29 (Accession #NP_742152.1) fused with a 6×His tag at the C-terminus.
Function Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Protein Name Interferon Lambda-1
Ifn-Lambda-1
Cytokine Zcyto21
Interleukin-29
Il-29
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-8854691
Cellular Localisation Secreted
Alternative Protein Names Interferon Lambda-1 protein
Ifn-Lambda-1 protein
Cytokine Zcyto21 protein
Interleukin-29 protein
Il-29 protein
IFNL1 protein
IL29 protein
ZCYTO21 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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