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  • 产品名称：Anti-AGTPBP1 antibody (320-520) (STJ115048)

  • 产品型号：STJ115048
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AGTPBP1 antibody (320-520) (STJ115048)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AGTPBP1 (320-520) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AGTPBP1
Gene ID: 23287
Uniprot ID: CBPC1_HUMAN
Immunogen Region: 320-520
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 320-520 of human AGTPBP1 (NP_056054.2).
Immunogen Sequence: PPEVDDVVDESDDNDDIDVE AENETENEDDLDQNFKNDDI ETDINKLKPQQEPGRTIEDL KMYEHLFPELVDDFQDYDLI SKEPKPFVFEGKVRGPIVVP TAGEETSGNSGNLRKVVMKE NISSKGDEGEKKSTFMDLAK EDIKDNDRTLQQQPGDQNRT ISSVHGLNNDIVKALDRITL QNIPSQTAPGFTAEMKKDCS L
Function Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.
Protein Name Cytosolic Carboxypeptidase 1
Atp/Gtp-Binding Protein 1
Nervous System Nuclear Protein Induced By Axotomy Protein 1 Homolog
Protein Deglutamylase Ccp1
Database Links Reactome: R-HSA-8955332
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Mitochondrion
Localizes In Both The Cytoplasm And Nuclei Of Interphase And Dividing Cells
Alternative Antibody Names Anti-Cytosolic Carboxypeptidase 1 antibody
Anti-Atp/Gtp-Binding Protein 1 antibody
Anti-Nervous System Nuclear Protein Induced By Axotomy Protein 1 Homolog antibody
Anti-Protein Deglutamylase Ccp1 antibody
Anti-AGTPBP1 antibody
Anti-CCP1 antibody
Anti-KIAA1035 antibody
Anti-NNA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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