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  • 产品名称：Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0013381)

  • 产品型号：STJE0013381
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0013381)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This AGTR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: AGTR1
Gene ID: 185
Uniprot ID: AGTR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Liver, lung, adrenal and adrenocortical adenomas.
Post Translational Modifications C-terminal Ser or Thr residues may be phosphorylated.
Function Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.
Protein Name Type-1 Angiotensin Ii Receptor
At1ar
At1br
Angiotensin Ii Type-1 Receptor
At1 Receptor
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Type-1 Angiotensin Ii Receptor ELISA kit
At1ar ELISA kit
At1br ELISA kit
Angiotensin Ii Type-1 Receptor ELISA kit
At1 Receptor ELISA kit
AGTR1 ELISA kit
AGTR1A ELISA kit
AGTR1B ELISA kit
AT2R1 ELISA kit
AT2R1B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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