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  • 产品名称：MASH1/Achaete-scute homolog 1 Blocking Peptide for STJ506351 peptide (STJ506352)

  • 产品型号：STJ506352-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
MASH1/Achaete-scute homolog 1 Blocking Peptide for STJ506351 peptide (STJ506352)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: MASH1/Achaete-scute homolog 1 Blocking Peptide for STJ506351 is synthetically produced from the 1175-225 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ASCL1
Gene ID: 429
Uniprot ID: ASCL1_HUMAN
Immunogen Region: 1175-225
Specificity: This blocking peptide is recommended for use in combination with MASH1/Achaete-scute homolog 1 antibody, STJ506351
Function Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Involved in the regulation of neuroendocrine cell development in the glandular stomach.
Peptide Name Achaete-Scute Homolog 1
Ash-1
Hash1
Class A Basic Helix-Loop-Helix Protein 46
Bhlha46
Database Links Reactome: R-HSA-9031628
Cellular Localisation Nucleus
Alternative Peptide Names Achaete-Scute Homolog 1 protein
Ash-1 protein
Hash1 protein
Class A Basic Helix-Loop-Helix Protein 46 protein
Bhlha46 protein
ASCL1 protein
ASH1 protein
BHLHA46 protein
HASH1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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