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  • 产品名称：Human ASGR1 (Asialoglycoprotein receptor 1) CLIA Kit (STJC0000294)

  • 产品型号：STJC0000294
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ASGR1 (Asialoglycoprotein receptor 1) CLIA Kit (STJC0000294)
详情介绍：
Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 18.75pg/mL
Detection Limit: 31.25~2000pg/mL
Short Description: This human ASGR1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: ASGR1
Gene ID: 432
Uniprot ID: ASGR1_HUMAN
Specificity: This kit recognizes Human ASGR1 in samples. No significant cross-reactivity or interference between Human ASGR1 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Expressed exclusively in hepatic parenchymal cells.
Post Translational Modifications Phosphorylated on a cytoplasmic Ser residue.
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Protein Name Asialoglycoprotein Receptor 1
Asgp-R 1
Asgpr 1
C-Type Lectin Domain Family 4 Member H1
Hepatic Lectin H1
Hl-1
Database Links Reactome: R-HSA-446203
Cellular Localisation Isoform H1a: Membrane
Single-Pass Type Ii Membrane Protein
Isoform H1b: Secreted
Alternative CLIA Names Asialoglycoprotein Receptor 1 CLIA kit
Asgp-R 1 CLIA kit
Asgpr 1 CLIA kit
C-Type Lectin Domain Family 4 Member H1 CLIA kit
Hepatic Lectin H1 CLIA kit
Hl-1 CLIA kit
ASGR1 CLIA kit
CLEC4H1 CLIA kit
Specificity This kit recognizes Human ASGR1 in samples. No significant cross-reactivity or interference between Human ASGR1 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 95-108 100
EDTA plasma(n=8) 95-106 100
Cell culture media(n=8) 98-111 104

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 97.51 248.10 917.17 90.71 252.00 1004.45
Standard deviation 11.22 25.08 65.21 9.27 28.17 106.87
CV (%) 11.51 10.11 7.11 10.22 11.18 10.64
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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