产品详情
简单介绍:
Anti-ANAPC5 antibody (1-250) (STJ29189)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IP |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ANAPC5 (1-250) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IHC-P 1:50-1:200 IP 1:50-1:100 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ANAPC5 |
Gene ID: | 51433 |
Uniprot ID: | APC5_HUMAN |
Immunogen Region: | 1-250 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_057321.2). |
Immunogen Sequence: | MASVHESLYFNPMMTNGVVH ANVFGIKDWVTPYKIAVLVL LNEMSRTGEGAVSLMERRRL NQLLLPLLQGPDITLSKLYK LIEESCPQLANSVQIRIKLM AEGELKDMEQFFDDLSDSFS GTEPEVHKTSVVGLFLRHMI LAYSKLSFSQVFKLYTALQQ YFQNGEKKTVEDADMELTSR DEGERKMEKEELDVSVREEE VSCSGPLSQKQAEFFLSQQA SLLKNDETKALTPASLQKE |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
Protein Name | Anaphase-Promoting Complex Subunit 5 Apc5 Cyclosome Subunit 5 |
Database Links | Reactome: R-HSA-141430 Reactome: R-HSA-174048 Reactome: R-HSA-174084 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-176407 Reactome: R-HSA-176408 Reactome: R-HSA-176409 Reactome: R-HSA-176412 Reactome: R-HSA-179409 Reactome: R-HSA-2467813 Reactome: R-HSA-2559582 Reactome: R-HSA-68867 Reactome: R-HSA-69017 Reactome: R-HSA-8853884 Reactome: R-HSA-9687136 Reactome: R-HSA-983168 |
Cellular Localisation | Nucleus Cytoplasm Cytoskeleton Spindle |
Alternative Antibody Names | Anti-Anaphase-Promoting Complex Subunit 5 antibody Anti-Apc5 antibody Anti-Cyclosome Subunit 5 antibody Anti-ANAPC5 antibody Anti-APC5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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