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  • 产品名称：Olig2 Blocking Peptide peptide (STJ504436)

  • 产品型号：STJ504436-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Olig2 Blocking Peptide peptide (STJ504436)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Olig2 Blocking Peptide is synthetically produced from the 136-156 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: OLIG2
Gene ID: 10215
Uniprot ID: OLIG2_HUMAN
Immunogen Region: 136-156
Immunogen: Synthetic peptide corresponding to Human Olig2 amino acids 136-156. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to a carrier protein using hetero-bifunctional cross linker for immunogen prepara
Tissue Specificity Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Function Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
Peptide Name Oligodendrocyte Transcription Factor 2
Oligo2
Class B Basic Helix-Loop-Helix Protein 1
Bhlhb1
Class E Basic Helix-Loop-Helix Protein 19
Bhlhe19
Protein Kinase C-Binding Protein 2
Protein Kinase C-Binding Protein Rack17
Cellular Localisation Nucleus
Cytoplasm
The Nls Contained In The Bhlh Domain Could Be Masked In The Native Form And Translocation To The Nucleus Could Be Mediated By Interaction Either With Class E Bhlh Partner Protein Or With Nkx2-2
Alternative Peptide Names Oligodendrocyte Transcription Factor 2 protein
Oligo2 protein
Class B Basic Helix-Loop-Helix Protein 1 protein
Bhlhb1 protein
Class E Basic Helix-Loop-Helix Protein 19 protein
Bhlhe19 protein
Protein Kinase C-Binding Protein 2 protein
Protein Kinase C-Binding Protein Rack17 protein
OLIG2 protein
BHLHB1 protein
BHLHE19 protein
PRKCBP2 protein
RACK17 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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