产品详情
简单介绍:
PDE11A Blocking Peptide peptide (Phospho) (S163) (STJ505832)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Phospho-PDE11A Blocking Peptide is synthetically produced from the 100-200 sequence about the S163 and is suitable for use in western blot applications. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Pde11a |
Gene ID: | 140928 |
Uniprot ID: | PDE11_RAT |
Immunogen Region: | 100-200 |
Immunogen: | Synthetic peptide taken within amino acid region 100-200 on rat PDE11A protein. Phosphorylated Ser 163. |
Tissue Specificity | Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate. |
Function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
Peptide Name | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a Camp And Cgmp Phosphodiesterase 11a |
Database Links | Reactome: R-RNO-418457 Reactome: -RNO-418555 |
Cellular Localisation | Cytoplasm Cytosol |
Alternative Peptide Names | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a protein Camp And Cgmp Phosphodiesterase 11a protein Pde11a protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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