产品详情
简单介绍:
Human TNFRSF11A/CD265 protein (Recombinant) (C-His) (STJP002626)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human TNFRSF11A/CD265-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TNFRSF11A |
Gene ID: | 8792 |
Uniprot ID: | TNR11_HUMAN |
Immunogen Region: | Ile30-Pro212 |
Immunogen: | Recombinant Human TNFRSF11A/CD265 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ile30-Pro212) of human RANK/TNFRSF11A/CD265 (Accession #Q9Y6Q6) fused with a 6×His tag at the C-terminus. |
Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 11a Osteoclast Differentiation Factor Receptor Odfr Receptor Activator Of Nf-Kb Cd Antigen Cd265 |
Database Links | Reactome: R-HSA-5668541 Reactome: R-HSA-5676594 |
Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Membrane Raft Isoform Rank-E5a: Cell Membrane |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 11a protein Osteoclast Differentiation Factor Receptor protein Odfr protein Receptor Activator Of Nf-Kb protein Cd Antigen Cd265 protein TNFRSF11A protein RANK protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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