产品详情
简单介绍:
PDE4D7 Blocking Peptide for STJ502341 peptide (STJ504651)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | PDE4D7 Blocking Peptide for STJ502341 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Pde4d |
Gene ID: | 238871 |
Uniprot ID: | PDE4D_MOUSE |
Specificity: | This blocking peptide is recommended for use in combination with PDE4D7 antibody, STJ502341 |
Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant. |
Tissue Specificity | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
Post Translational Modifications | Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation. |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
Peptide Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4d Dpde3 |
Database Links | Reactome: R-MMU-180024 Reactome: -MMU-418555 |
Cellular Localisation | Cytoplasm Membrane Cytoskeleton Microtubule Organizing Center Centrosome Apical Cell Membrane Colocalized With Shank2 To The Apical Membrane Of Colonic Crypt Cells Found In The Soluble Fraction Associated With Membranes And Associated With The Cytoskeleton And The Centrosome |
Alternative Peptide Names | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4d protein Dpde3 protein Pde4d protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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