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  • 产品名称：Anti-APOO antibody [2F1] (STJ97843)

  • 产品型号：STJ97843
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-APOO antibody [2F1] (STJ97843)
详情介绍：
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-MICOS complex subunit MIC26 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 2F1
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOO
Gene ID: 79135
Uniprot ID: MIC26_HUMAN
Specificity: ApoO Monoclonal Antibody detects endogenous levels of ApoO protein.
Immunogen: Purified recombinant fragment of ApoO expressed in E. Coli.
Post Translational Modifications O-glycosylation.glycosaminoglycan of chondroitin-sulfate type.
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function. Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL.
Protein Name Micos Complex Subunit Mic26
Apolipoprotein O
Micos Complex Subunit Mic23
Protein Fam121b
Database Links Reactome: R-HSA-8949613
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Secreted
Mitochondrion
Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Exists In Three Distinct Forms: A Glycosylated And Secreted Form
An Er/Golgi-Resident Form And A Non-Glycosylated Mitochondrial Form
Alternative Antibody Names Anti-Micos Complex Subunit Mic26 antibody
Anti-Apolipoprotein O antibody
Anti-Micos Complex Subunit Mic23 antibody
Anti-Protein Fam121b antibody
Anti-APOO antibody
Anti-FAM121B antibody
Anti-MIC23 antibody
Anti-MIC26 antibody
Anti-My025 antibody
Anti-UNQ1866 antibody
Anti-PRO4302 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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