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  • 产品名称：PP2A-beta Positive Control for STJ505948 peptide (STJ505731)

  • 产品型号：STJ505731-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
PP2A-beta Positive Control for STJ505948 peptide (STJ505731)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PP2A-beta Positive Control for STJ505948 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PPP2R5B
Gene ID: 5526
Uniprot ID: 2A5B_HUMAN
Specificity: This is positive control is recommended for use in combination with PP2A-beta antibody STJ505948.
Immunogen: Purified Serine/Threonine-Protein Phosphatase 2A 56 kDa regulatory Beta subunit.
Post Translational Modifications Ubiquitinated by E3 CUL3-KLHL15 complex.this modification leads to proteasomal degradation.
Function As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
Peptide Name Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Beta Isoform
Pp2a B Subunit Isoform B'-Beta
Pp2a B Subunit Isoform B56-Beta
Pp2a B Subunit Isoform Pr61-Beta
Pp2a B Subunit Isoform R5-Beta
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-195253
Reactome: R-HSA-196299
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-381038
Reactome: R-HSA-389513
Reactome: R-HSA-432142
Reactome: R-HSA-4641262
Reactome: R-HSA-5339716
Reactome: R-HSA-5358747
Reactome: R-HSA-5358749
Reactome: R-HSA-5358751
Reactome: R-HSA-5358752
Reactome: R-HSA-5467337
Reactome: R-HSA-5467340
Reactome: R-HSA-5467348
Reactome: R-HSA-5663220
Reactome: R-HSA-5673000
Reactome: R-HSA-5675221
Reactome: R-HSA-6811558
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Cytoplasm
Alternative Peptide Names Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Beta Isoform protein
Pp2a B Subunit Isoform B'-Beta protein
Pp2a B Subunit Isoform B56-Beta protein
Pp2a B Subunit Isoform Pr61-Beta protein
Pp2a B Subunit Isoform R5-Beta protein
PPP2R5B protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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